Hey @DevWcp,
This could be done but would require Operations Hub Professional, this allows you to trigger webhooks from workflows. The flow would be that when a custom object (or any object) property is updated a webhook is triggered from a workflow to a desired service. You configure the payload sent from HubSpot and the data returned can then be used as required.
I’ve done similar for email validation using a service called Kickbox and also for phone number validation using a service called NumVerify.
Do you have a particular service you are thinking of using for the validation?