For customer service teams that are not available 24/7, an auto reply message that could be set for each inbox afterhours would help set the expectation as to when a customer would receive a reply to their inquiry.
We are migrating to full use of Hubspot in November and this is a feature in our current email system, HelpScout. For each of our team's inboxes, a customized reply is able to be created and both times of day and days of week selected for when we want it to reply. On holiday's, we are able to easily modify the times/ days.
Our team would want the autoreply sent from 5pm - 9am, M-F and all day Sat & Sun.