@ekt there is not an official way to remove it because many built-in HubSpot modules require it. However, you can move it to the footer to increase page performance.
I'm not entirely sure you can safely disable it without losing functionality native to how the CMS operates with jquery. However, I'm going to throw out a guess, in hopes that it might help.
<script>
// remove all jquery event listeners
$("*").off();
// set jquery to undefined
$ = jQuery = undefined;
</script>