Hi @HDawkins ,
Totally get your predicatment here. You can only choose ‘list membership’ or ‘lifecycle’ stage at the moment for smart content in an email. Since there are so many combinations of courses interests; just course 1, just course 2, courses 1 & 2, courses 1 & 6 etc this would be a lot of combinations.
Another suggestion could be to simply have 10 lists and have 10 different sections on your email with smart rules. Each section corresponds to a list so the default is blank but if you are on Course list 1 then section one is filled in, if not, it’s blank and so on.
It might take some creative design to make sure the spacing doesn’t look strange but just a thought!